Insulin injections are linked to weight gain and the loss of control of blood sugar levels

Study reveals weight loss program synced with organic clock might substitute problematic diabetes therapy.

Washington: While the type of meals one eats and even the order through which it’s consumed can have an effect on the well being of a person. A brand new examine finds starch-rich breakfast consumed early in the morning coupled with a small dinner might substitute insulin injections and different diabetes drugs for a lot of diabetics.

Type 2 diabetics inject themselves with insulin, a hormone that regulates the motion of sugar into liver, muscle and fats cells, up to 4 instances a day. But insulin injections are linked to weight gain and the loss of control of blood sugar levels. This triggers a vicious cycle of increased insulin doses, steady weight gain, the next incidence of heart problems and different issues.

According to the new analysis, our metabolism and organic clock are optimised for consuming in the morning and for fasting throughout the night and night time, once we are supposed to be asleep. Prof. Daniela Jakubowicz of TAU’s Sackler Faculty of Medicine and Wolfson Medical Center’s Diabetes Unit stated, “But the usual diet recommended for type 2 diabetes consists of several small meals evenly distributed throughout the day, for example, three meals and three snacks daily, including a snack before going to sleep to prevent a drop in sugar levels during the night.”

The analysis was revealed in the journal Diabetes Care. According to Prof. Jakubowicz “The traditional diabetic diet specifies six small meals spread throughout the day. But our research proposes shifting the starch-rich calories to the early hours of the day. This produces a glucose balance and improved glycemic control among type 2 diabetics.”

Thus explaining the cause behind this principle of weight loss program as “We believe that through this regimen it will be possible for diabetics to significantly reduce or even stop the injections of insulin, and most of the anti-diabetic medications, to achieve excellent control of glucose levels.”

Prof. Jakubowicz added.”But the ‘6M-diet,’ as that is known as, has not been efficient for sugar control, so diabetics require extra treatment and insulin. And insulin injections lead to weight gain, which additional will increase blood sugar levels,”

The researchers studied 29 kind 2 diabetes individuals and in contrast a brand new “3M-diet,” extra in alignment with our organic clock, with a control group on the conventional 6M-diet. The experimental 3M-diet contains a meal of bread, fruits, and sweets in the early hours of the morning; a considerable lunch; and a small dinner particularly missing starches, sweets, and fruits.

The group on the conventional 6M-diet didn’t lose weight and didn’t expertise any enchancment of sugar levels, requiring a rise in treatment and insulin doses. But the group on the 3M-diet not solely misplaced weight but in addition skilled considerably improved sugar levels.

Prof. Jakubowicz is of the view, “In addition, the 3M-diet improved the expression of biological clock genes. This suggests that 3M-diet is not only more effective in controlling diabetes. It may also prevent many other complications such as cardiovascular disease, ageing, and cancer, which are all regulated by the biological clock genes.”

The upregulation of the organic clock gene expression in the 3M-diet is perhaps the mechanism behind its success, because it enhances insulin secretion and improves sugar supply into the muscle tissues, making a balanced daytime and nocturnal glucose metabolism. The researchers are now investigating the position sure proteins play in breakfast meals consumed by diabetics.


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